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Brave new world

Brave new world : On the India-European Free Trade Association agreement and IPR

India must invest in fundamental research to be able to develop reliable drugs 

Expectations are high that a free trade-agreement involving India and the European Free Trade Association (EFTA) is close to fruition . However, a bone of contention relates to intellectual property rights , and has persisted as an issue since 2008. Switzerland and Norway, which are prominent members of EFTA, host several of the pharmaceutical and biotechnology companies that are responsible for several of the drugs and therapeutics that underpin health care globally. The nature of the pharma industry — it costs much to discover a useful effective drug and relatively little to make generic copies of it — with demand that is far disproportionate to affordability , means that there is a constant tussle between the inventors and the generic-drug companies. Patenting , or an exclusive monopoly for a fixed number of years to originators and a reciprocal right by governments to issue directions for ‘compulsory licensing,’ thereby selectively breaking such monopolies in the interest of public health, has brokered the peace and sustained the global pharma industry for decades . But new legal innovations such as data exclusivity continue to inveigle themselves in free trade negotiations. Under this provision, all the clinical-trial data that concerns the safety and efficacy of a drug generated by the originator firm becomes proprietary and out of bounds for a minimum period of six years. Permission to make a generic is possible if a country’s regulator can rely-on supplied clinical trial data to approve a drug. For this, generic makers usually rely on the originator’s published data.

The principle of data exclusivity is present among European countries as well as in agreements involving many developing countries. Were it to take effect in India, it could significantly hinder India’s drug industry which is also a major exporter of affordable drugs. Indian officials have rejected data exclusivity as a point of negotiations in the FTA, though leaked drafts of the agreement suggest that it is alive . However, India’s rise up the drug manufacturing chain in the last few decades means that it must invest in an ecosystem that can conduct ethical drug trials and make new molecules and therapeutics from scratch . The paradigm that drug development will always be expensive and confined to the West need not be permanent, as was seen in the development of several novel technology approaches to developing vaccines in India during the COVID-19 pandemic. But as preparation, India must invest substantially more in fundamental research to incubate the local drug industry into the future.

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Sustain
(verb) – continue, carry on, keep, maintain, prolong, preserve

बनाए रखना

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Decade
(noun) – A period of 10 years

दशक

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Monopoly (noun) – Exclusive control, total dominance, complete ownership, sole command, cartel

एकाधिकार

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Tussle (noun) – scuffle, brawl, fight, skirmish, conflict

संघर्ष

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Broker (verb) – Negotiate, arrange, mediate, orchestrate, facilitate,

मध्यस्थता करना

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Affordable (adjective) – Inexpensive, budget-friendly, economical, reasonably priced, cost-effective.

सस्ती

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Fruition (noun) – Realization, fulfillment, completion, achievement, actualization

साकार होना

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Substantially (adverb) – Significantly, considerably, greatly, markedly, extensively

काफी

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Rely (on) (verb) – Depend on, count on, bank on, trust in, lean on

निर्भर करना

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Prominent (adjective) – Notable, outstanding, important, significant, distinguished

प्रमुख

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Novel (adjective) – New, original, innovative, fresh, unique

नया

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Hinder (verb) – Obstruct, impede, inhibit, hamper, block

बाधा डालना

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Brave new world (phrase) – used to refer, often ironically, to a new and hopeful period in history resulting from major changes in society.

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Drug (noun) – Medication, medicine, pharmaceutical, remedy, cure

दवा

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Free trade agreement (noun) – A pact between two or more nations to reduce barriers to imports and exports among them

स्वतंत्र व्यापार समझौता

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Bone of contention (phrase) – Subject of dispute, point of disagreement, matter of contention, issue, problem विवाद का कारण

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Intellectual property rights (IPR) (noun) – The rights given to persons over the creations of their minds; they usually give the creator an exclusive right over the use of his/her creation for a certain period of time.

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Persist (verb) – Continue, endure, remain, last, persevere

बने रहना

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Underpin (verb) – Support, reinforce, strengthen, fortify, bolster

मजबूती प्रदान करना

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Generic (adjective) – Non-branded, universal, common, standard, general

सामान्य

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Disproportionate (adjective) – Unequal, unbalanced, inordinate, excessive, unreasonable

असमान

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Affordability (noun) – The state of being affordable; inexpensive, reasonably priced

किफायत

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Patenting (noun) – The process of obtaining a patent, which is a set of exclusive rights granted by a sovereign state to an inventor or assignee for a limited period of time in exchange for detailed public disclosure of an invention.

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Reciprocal (adjective) – Mutual, corresponding, complementary, equivalent, matching

पारस्परिक

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Thereby (adverb) – As a result of that, by that means, thus, therefore

इसके द्वारा

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Exclusivity (noun) – The state of being exclusive; a privilege or right to be the only one to have, do, or enjoy something

विशेषाधिकार

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Inveigle (verb) – Persuade, entice, lure, seduce, tempt

फुसलाना

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Efficacy (noun) – Effectiveness, efficiency, potency, power, capability

प्रभावकारिता

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Proprietary (adjective) – Owned, private, patented, exclusive, trademarked

स्वामित्व/ मालिकाना

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Out of bounds (phrase) – Forbidden, prohibited, off-limits, restricted, banned

प्रतिबंधित

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Take effect (phrase) – Begin to operate, become active, come into force, apply, be applied

लागू होना

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Alive (adjective) – Living, existent, active, operational, functioning

जीवित

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Ecosystem (noun) – A biological community of interacting organisms and their physical environment. पारिस्थितिकी तंत्र

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From scratch (phrase) – From the beginning, from the start, from nothing, anew, afresh

शुरू से

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Paradigm (noun) – Model, pattern, example, standard, prototype

प्रतिमान

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Confine (to) (verb) – Limit, restrict, keep within limits, constrain, bind

सीमित करना

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The West (noun) – Referring to the Western world, typically including cultures and countries in Europe and North America

पश्चिम देश

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Incubate (verb) – To develop or grow under favorable conditions; in business, it often refers to supporting startups until they become viable