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Taking on TB

Express View: Taking on TB

A major challenge for any country’s TB elimination programme is to make sure that cases are reported. A patient falling outside the screening and treatment network is not only harmful to the individual concerned , it also exposes her contacts to the risk of infection.

Under-reporting of cases has, for long, been a major hurdle for India’s anti-TB programme. It’s, therefore, assuring that the latest factsheet on the disease in the country, the India TB Report 2024, shows that the gap between the estimated number and actual TB cases is closing. India has attained its 2023 target of initiating treatment in 95 per cent of patients diagnosed with the infection.

The government has set an ambitious target to eliminate the disease in the country by next year. Despite the anti-TB programme’s appreciable success in the past two years, the country does not seem to be on-course to attain this target. The disease’s multi-drug resistant (MDR) version has assumed epidemic proportions.

The latest India TB Report shows significant progress in charting this severe version of the disease. Close to 60 per cent of those diagnosed were offered a test to check whether their infection was resistant to the first-line drugs , an increase from 25 per cent in 2015.

In the coming months, the health authorities should reach out to more patients to ascertain the numbers of those whose illness requires the administration of second-line-drugs .

In recent years, experts have been recommending the use of molecular testing because microscopy cannot detect all MDR cases. But by all accounts , this state-of-the-art diagnostics is still not the predominant testing method in the country.

Although several drug regimens are available for MDR-TB, these are demanding on patients. A growing body of scholarship shows that less than 60 per cent of patients who require a second-line treatment complete the full course of medicines. Experts, therefore, suggest a transition to the short-duration drug, bedaquiline .

India’s patent office’s decision, last year, to not renew Johnson and Johnson’s copyright on this drug should enable the domestic industry to step in and develop cheaper generic versions . In recent years, mental healthcare has increasingly been seen as a critical part of TB treatment and epidemiologists have been advising physicians to handhold patients through the exacting therapy — this rarely happens in the country. Though TB can affect all social classes, records show that the poor, slum dwellers , and HIV/AIDS patients are the most affected. In the coming months, the country’s planners should deploy a combination of state of the art technology and humane methods to build on the gains of last year.

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Severe
(adjective) – harsh, serious, hard, tough, grave

गंभीर

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Step in
(phrasal verb) –  interfere, intervene, get involved, take action

हस्तक्षेप करना

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Screening
(noun) – Inspection, testing, diagnosis, checking

जाँच

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Predominant
(adjective) – dominant, main, primary, leading

प्रमुख

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Elimination (noun) – Removal, eradication, exclusion, dismissal, हटाना

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Expose (verb) – reveal, unveil, unmask, display

प्रकट करना

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Ambitious (adjective) – aspiring, ambitious, eager; desirous, avid, zealous

महत्वाकांक्षी

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Transition (noun) – Change, shift, move, passage, transformation 

परिवर्तन

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Initiate (verb) – Begin, start, commence, inaugurate, launch

शुरू करना

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Ascertain (verb) – Determine, find out, establish, verify, confirm

पता लगाना

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Deploy (verb) – Utilize, employ, use, apply, mobilize

उपयोग करना

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Humane (adjective) – Compassionate, kind, considerate, sympathetic, benevolent

मानवीय

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Take on (phrasal verb) – Compete against, oppose, challenge, confront, face, fight

मुक़ाबला करना

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Concerned (adjective) – Affected, involved, related, be about

संबंधित

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Attain (verb) – Achieve, reach, accomplish, obtain, acquire

हासिल करना

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Diagnose (verb) – Identify, detect, determine, recognize, ascertain

रोग का निर्णय करना

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Eliminate (verb) – Remove, eradicate, get rid of, abolish, delete

खत्म करना

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Appreciable (adjective) – Considerable, significant, substantial, noticeable, marked  

महत्वपूर्ण

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On course to (phrase) – On track to, heading towards, en route to, aiming for, directed towards

की ओर बढ़ते हुए

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Multi-drug resistant (MDR) (noun) – A type of bacteria or virus that is resistant to multiple antibiotics or antiviral drugs

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Assume (verb) – Take on, adopt, acquire, embrace, accept

अपनाना

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Epidemic (adjective) – Widespread, rampant, pervasive, extensive, prevalent

महामारी, व्यापक

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Chart (verb) – Map, outline, plan, plot, sketch

चार्ट बनाना, योजना बनाना

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Resistant (adjective) – Immune, impervious, unaffected, unyielding, insusceptible

प्रतिरोधी

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first-line drugs (noun) – Primary medications used for treatment

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Reach out (phrasal verb) – Contact, communicate, get in touch, connect, approach

संपर्क करना, पहुंचना

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Illness (noun) – Sickness, disease, ailment, disorder, condition

रोग

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Administration (noun) – the act of giving someone something (i.e. drugs)

देना (दवाओं)

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Second-line drugs (noun) – Alternative medications used when first-line drugs are ineffective

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Microscopy (noun) – The use of a microscope to view small objects

सूक्ष्मदर्शी विज्ञान

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By all accounts (phrase) – According to everyone, universally acknowledged, without exception

सभी के अनुसार

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State-of-the-art (adjective) – Cutting-edge, advanced, modern, latest, up-to-date

अत्याधुनिक

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Diagnostic (noun) – A tool or test used to identify a disease or condition

परीक्षण

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Regimen (noun) – Routine, regime, schedule, plan, program

नियमित दिनचर्या

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Bedaquiline (noun) – A medication used to treat multi-drug resistant tuberculosis

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Generic version (noun) – A non-branded version of a medication

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Epidemiologist (noun) – A scientist who studies the patterns, causes, and effects of health and disease conditions in defined populations

महामारी विज्ञानी

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Handhold (verb) – Guide, assist, help, support, aid

सहायता करना, मार्गदर्शन करना

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Exacting (adjective) – Demanding, rigorous, strict, challenging, tough

कठिन

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Slum dweller (noun) – A person who lives in a slum

झुग्गी बस्ती का निवासी

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Build on (phrasal verb) – Expand, develop, enhance, improve, augment

विकसित करना